Jane Metcalfe

Executive Chair


Jane Metcalfe is executive chair of the Human Immunome Project. As an entrepreneur, editor, publisher, investor, and advisor, she is passionate about harnessing  transformative ideas to create strong brands, rapidly grow businesses, and lead healthy, creative, mission-driven organizations.

Metcalfe is the co-founder and former president of Wired Ventures, Inc., a diversified media company whose businesses included Wired Magazine (US, UK, and Japanese editions), Wired Digital, and Wired Books. More recently, she was the CEO and founder of proto.life (formerly known as NEO.LIFE), a weekly newsletter, website, book, and events company that tracked how digital tools and an engineering mindset are revolutionizing human biology. Prior to that, Metcalfe made chocolate on a pier in San Francisco as the President of TCHO Chocolate, whose TCHOSource program continues to transform the lives of cacao farmers in Latin America and Africa.

In addition to her work with the Human Immunome Project, Metcalfe is also co-chair of the Futures Council of the Focused Ultrasound Foundation and advises various startups.