Dr. Mark M. Davis is the Director of the Stanford Center for Human Systems Immunology, a Professor of Microbiology and Immunology, and a Howard Hughes Medical Institute Investigator. He received a BA from Johns Hopkins University and a PhD from the California Institute of Technology. He later was a postdoctoral fellow and staff fellow at the Laboratory of Immunology at NIH and then became a faculty member in the Department of Microbiology and Immunology at Stanford University School of Medicine, where he remains today. Dr. Davis is well known for identifying many of the T-cell receptor genes, which are responsible for the ability of these cells to recognize a diverse repertoire of antigens. Other work in his laboratory pioneered studies of the biochemistry, genetics and cell biology of these molecules and T lymphocytes generally, which play a key role in orchestrating immune responses. His group has developed many new technologies to enable human immunology studies, including the widely used peptide-MHC tetramers and most recently spheromers to enable the labeling of antigen specific T cells, the first high throughput single T cell analysis methodology, the GLIPH program to analyze T cell specificities directly from sequence data and, most recently, a simple method to create immune organoids from tonsils or spleens to allow human immune responses to be analyzed in vitro.