Pioneering a New Era
of Human Health

For all people, across all diseases

The Next Frontier

For the first time ever, scientists at the Human Immunome Project are combining systems biology with artificial intelligence to understand one of the greatest remaining frontiers of human health, the human immune system.

Modeled after the Human Genome Project, which has transformed biomedical research, the Human Immunome Project (formerly known as the Human Vaccines Project) is seeking to transform how we fight our most devastating diseases by unlocking the mechanisms of human immunity — accelerating the development of new vaccines, diagnostics, and treatments.


Vaccines lead to a drastic decline in devastating diseases, disability, inequity and death worldwide. Many of us are here today because we or previous generations were vaccinated.​ But vaccine research is increasingly held back by the limits of scientific knowledge.

Today, the diseases we battle are much more insidious and biologically complex than those conquered in the past. Despite decades of work and billions in investment, vaccines for HIV, tuberculosis, and cancers have evaded scientists’ best efforts and humanity remains unprepared against the next pandemic.

A new approach is necessary now, one that is rooted in identifying and understanding the common elements of the human immune system that overlap across global populations and that allows us to harness this knowledge and the collective intelligence of scientists worldwide toward prevention and control of a range of diseases.


Until now, decoding the immune system was thought impossible. Breakthrough advances in biomedicine merged with AI allow us for the first time to understand our own immunity to disease – and change the future of health.

Through our innovative business model and global consortium, the Human Immunome Project is putting these technologies in the hands of the world’s top scientists.

Together with our worldwide network of partners, we are compiling the biggest dataset of biomedicine at a population scale. ​We will use this data to create the first AI model of the human immune system, which will help us speed up the testing process and make the development of vaccines and treatments faster, cheaper and more effective.

In 2022, the Human Immunome Project convened the Human Immunome AI Summit to map the next frontier in human health: the development of the first-ever AI model of the human immunome. The Summit will be followed by a series of conferences all around the globe to refine the strategic plan culminating with a global scientific and advocacy campaign.


Our goal is nothing short of transformative: enabling people to live much healthier — and longer — lives.

The immune system — an intricate network of cells, tissues, and organs — is the human body’s primary mechanism for staying healthy. Decoding it should be central to our efforts to understand and fight disease, whether non-communicable or infectious. We see a world in which we can:

  • Prevent pandemics before they spread.
  • Develop effective vaccines within weeks, not years.
  • Treat cancers, Alzheimer’s, heart disease, diabetes and other non-communicable diseases.
  • Protect those most vulnerable to disease: newborns, aging adults and those living in developing countries.

We are working to make disease prevention, diagnosis, and treatment effective for all people, across all diseases.

Our Initiatives

We established key initiatives and partnerships to focus on those most at risk of disease and the hardest to protect.


Protecting our rapidly aging global society, with the Harvard T.H. Chan School


Preventing the next pandemic by developing the first universal coronavirus vaccine


Reducing infant
mortality by half by deciphering effective immunity in newborns